Description
Paired box 7 (PAX7) gene regulates the conversion of muscle satellite cells into myogenic cells and participates in multi-step processes in myogenesis. Expression levels of PAX7 are decisive for its regulatory function.PAX7 encodes a transcription factor essential in neural crest formation, myogenesis, and pituitary lineage specification. PAX7, a member of the PAX transcription factor gene family, is normally expressed at high levels during development in the neural tube and in skeletal muscle precursor cells.The human PAX7 gene encodes a protein containing a domain homologous to the Drosophila paired box first described in three segmentation genes